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The Aspirin Factor

SOMETIMES I cannot believe what medical science and technology have reached today. But surprises are many, perhaps too many to count, or to seek in order to appreciate the exact number. One of these medical surprises is aspirin. Yes, aspirin, or what we know chemically as acetylsalicylic acid. It is originally used as a pain-reliever, a fever-reducer, and an anti-inflammatory. But many decades ago, it came to be used in certain cardiovascular conditions, such as heart attacks, strokes, and blood clotting disorders, because of its anti-platelet effect. It produces a substance called thromboxane, which under normal conditions binds platelet molecules together, making it unavailable to create blood clots that can cause recurrence of heart attack, for instance. Just recently, in its July 23 issue, the Journal of the American Medical Association (Jama), published a study involving three researchers—Andrew Chan, Shuji Ogino, and Charles Fuchs. Chan is a gastroenterologist at the Massachuse